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InnateDB Protein
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IDBP-242884.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC35B2
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Protein Name
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solute carrier family 35, member B2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000377399
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InnateDB Gene
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IDBG-89538 (SLC35B2)
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Protein Structure
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| Function |
Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways. {ECO:0000269PubMed:12716889}.
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| Subcellular Localization |
Golgi apparatus membrane {ECO:0000269PubMed:12716889}; Multi-pass membrane protein {ECO:0000269PubMed:12716889}.
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| Disease Associations |
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| Tissue Specificity |
Highly expressed in the placenta, pancreas, mammary gland and skeletal muscle. Weakly or not expressed in colon, heart and prostate. {ECO:0000269PubMed:12716889}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q8TB61
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
347734
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| UniGene |
Hs.661026
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| RefSeq |
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| HUGO |
HGNC:16872
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| OMIM |
610788
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| CCDS |
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| HPRD |
11576
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4