Version 5.4
Homo sapiens Protein: FDX1L
Summary
InnateDB Protein IDBP-243075.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FDX1L
Protein Name ferredoxin 1-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377311
InnateDB Gene IDBG-730584 (FDX1L)
Protein Structure
UniProt Annotation
Function Essential for heme A and Fe/S protein biosynthesis. {ECO:0000269PubMed:20547883}.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:20547883}. Mitochondrion matrix {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed, with highest levels in testis, kidney and brain (at protein level). {ECO:0000269PubMed:20547883}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0009055 electron carrier activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID
InterPro IPR001041 2Fe-2S ferredoxin-type domain
IPR001055 Adrenodoxin
PFAM PF00111
PRINTS PR00355
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P4F2
PhosphoSite PhosphoSite-Q6P4F2
TrEMBL
UniProt Splice Variant
Entrez Gene 112812
UniGene Hs.654865
RefSeq NP_001026904
HUGO HGNC:30546
OMIM 614585
CCDS CCDS32905
HPRD 14465
IMGT
EMBL BC063460
GenPept AAH63460

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca