InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FAM50A

Summary

InnateDB Protein

IDBP-243288.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FAM50A

Protein Name

family with sequence similarity 50, member A

Synonyms

9F; DXS9928E; HXC-26; HXC26; XAP5;

Species

Homo sapiens

Ensembl Protein

ENSP00000377225

InnateDB Gene

IDBG-91559 (FAM50A)

Protein Structure

UniProt Annotation

Function

May be a DNA-binding protein or transcriptional factor. {ECO:0000269PubMed:9339379}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in all tissues examined. Mostly abundant in fetal brain, liver and kidney; in the adult, high levels were also observed in heart, skeletal muscle, spleen, thymus, prostate and small intestine. {ECO:0000269PubMed:9339379}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0007283

spermatogenesis

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR007005 XAP5 protein

PFAM

PF04921

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q14320

PhosphoSite

PhosphoSite-Q14320

TrEMBL

B0S8I6

UniProt Splice Variant

Entrez Gene

9130

UniGene

Hs.54277

RefSeq

NP_004690

HUGO

HGNC:18786

OMIM

300453

CCDS

CCDS14751

HPRD

02349

IMGT

EMBL

AD001530 AK293119 AK313697 BC000028 BC015499 BX936365 CH471172 D83260 D83389 L44140

GenPept

AAA92649 AAB81663 AAH00028 AAH15499 BAA11871 BAA11907 BAF85808 BAG36444 CAI43193 EAW72708