InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DBN1

Summary

InnateDB Protein

IDBP-243372.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DBN1

Protein Name

drebrin 1

Synonyms

D0S117E;

Species

Homo sapiens

Ensembl Protein

ENSP00000377195

InnateDB Gene

IDBG-60129 (DBN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 88 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	88 [view]
Protein-Protein	86 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005522	profilin binding

Biological Process

GO:0007015	actin filament organization
GO:0048168	regulation of neuronal synaptic plasticity
GO:0050773	regulation of dendrite development

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005938	cell cortex
GO:0015629	actin cytoskeleton
GO:0030425	dendrite
GO:0042641	actomyosin

Protein Structure and Domains

PDB ID

InterPro

IPR002108 Actin-depolymerising factor homology domain

PFAM

PF00241

PRINTS

PIRSF

SMART

SM00102

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q16643

PhosphoSite

PhosphoSite-Q16643

TrEMBL

D6RFI1

UniProt Splice Variant

Entrez Gene

1627

UniGene

Hs.614285

RefSeq

XP_005265884

HUGO

HGNC:2695

OMIM

126660

CCDS

HPRD

00545

IMGT

EMBL

AC145098 AK314645 AL110225 BC000283 BC007281 BC007567 BC114553 D17530 U00802

GenPept

AAA16256 AAH00283 AAH07281 AAH07567 BAA04480 BAG37207 CAB53683