Homo sapiens Protein: PTGFRN
Summary
InnateDB Protein IDBP-244085.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTGFRN
Protein Name prostaglandin F2 receptor negative regulator
Synonyms CD315; CD9P-1; EWI-F; FPRP; SMAP-6;
Species Homo sapiens
Ensembl Protein ENSP00000376899
InnateDB Gene IDBG-101422 (PTGFRN)
Protein Structure
UniProt Annotation
Function Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0034389 lipid particle organization
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00406
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P2B2
PhosphoSite PhosphoSite-Q9P2B2
TrEMBL Q9H3U3
UniProt Splice Variant
Entrez Gene 5738
UniGene Hs.710711
RefSeq NP_065173
HUGO HGNC:9601
OMIM 601204
CCDS CCDS890
HPRD 03124
IMGT
EMBL AB014734 AB037857 AK074637 AL157904 AL445231 BC152454
GenPept AAI52455 BAA92674 BAB20271 BAC11104 CAH71960 CAI22650