InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADAMTSL2

Summary

InnateDB Protein

IDBP-244393.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAMTSL2

Protein Name

ADAMTS-like 2

Synonyms

GPHYSD1;

Species

Homo sapiens

Ensembl Protein

ENSP00000376781

InnateDB Gene

IDBG-91475 (ADAMTSL2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013273 Peptidase M12B, ADAM-TS

PFAM

PF00090
PF05986
PF08686

PRINTS

PR01857

PIRSF

SMART

SM00209

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-BAA25531

TrEMBL

B1B0D4

UniProt Splice Variant

Entrez Gene

9719

UniGene

Hs.632697

RefSeq

XP_005272294

HUGO

HGNC:14631

OMIM

612277

CCDS

HPRD

11096

IMGT

EMBL

AB011177 BC050544 BX324209 BX629352 BX649571

GenPept

AAH50544 BAA25531 CAI17317 CAI18773 CAI23592