Version 5.4
Homo sapiens Protein: IGF1
Summary
InnateDB Protein IDBP-244700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGF1
Protein Name insulin-like growth factor 1 (somatomedin C)
Synonyms IGF-I; IGF1A; IGFI;
Species Homo sapiens
Ensembl Protein ENSP00000376638
InnateDB Gene IDBG-53609 (IGF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0008083 growth factor activity
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR016179 Insulin-like
IPR022341 Insulin-like growth factor I
IPR022350 Insulin-like growth factor
IPR022352 Insulin family
PFAM PF00049
PRINTS PR02005
PR02002
PR00276
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q13429
UniProt Splice Variant
Entrez Gene 3479
UniGene Hs.708628
RefSeq
HUGO HGNC:5464
OMIM 147440
CCDS
HPRD 00936
IMGT
EMBL AC010202 U40870
GenPept AAA96152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca