Version 5.4
Homo sapiens Protein: NT5DC3
Summary
InnateDB Protein IDBP-244763.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NT5DC3
Protein Name 5'-nucleotidase domain containing 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000376615
InnateDB Gene IDBG-54027 (NT5DC3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in brain, placenta, skeletal muscle, pancreas, testis, uterus, and small intestine. Reduced expression in pancreatic cancer cells. {ECO:0000269PubMed:15547748}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR008380 HAD-superfamily hydrolase, subfamily IG, 5\'-nucleotidase
IPR016695 Purine 5\'-nucleotidase
IPR023214 HAD-like domain
PFAM PF05761
PF00702
PF08282
PF13419
PRINTS
PIRSF PIRSF017434
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UY8
PhosphoSite PhosphoSite-Q86UY8
TrEMBL
UniProt Splice Variant
Entrez Gene 51559
UniGene Hs.626192
RefSeq NP_001026871
HUGO HGNC:30826
OMIM 611076
CCDS CCDS41824
HPRD 18241
IMGT
EMBL AB032773 AB032786 AK002128 BC052293 CH471054
GenPept AAH52293 BAA92095 BAA93053 BAA93086 EAW97716

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca