InnateDB Protein
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IDBP-245394.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NUDT14
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Protein Name
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nudix (nucleoside diphosphate linked moiety X)-type motif 14
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000376349
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InnateDB Gene
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IDBG-23192 (NUDT14)
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Protein Structure
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Function |
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP- mannose.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:12429023}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000086
NUDIX hydrolase domain
IPR004385
Nucleoside diphosphate pyrophosphatase
IPR015797
NUDIX hydrolase domain-like
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PFAM |
PF00293
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O95848
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PhosphoSite |
PhosphoSite-O95848
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
256281
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UniGene |
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RefSeq |
NP_803877
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HUGO |
HGNC:20141
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OMIM |
609219
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CCDS |
CCDS10000
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HPRD |
14847
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IMGT |
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EMBL |
AB087802
AF111170
AL512355
BC041584
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GenPept |
AAD15563
AAH41584
BAC65455
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