InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EEF1B2

Summary

InnateDB Protein

IDBP-246098.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EEF1B2

Protein Name

eukaryotic translation elongation factor 1 beta 2

Synonyms

EEF1B; EEF1B1; EF1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000376056

InnateDB Gene

IDBG-79451 (EEF1B2)

Protein Structure

UniProt Annotation

Function

EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	55 [view]
Protein-Protein	54 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003746	translation elongation factor activity
GO:0005515	protein binding

Biological Process

GO:0006412	translation
GO:0006414	translational elongation
GO:0010467	gene expression
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005829	cytosol
GO:0005853	eukaryotic translation elongation factor 1 complex

Protein Structure and Domains

PDB ID

InterPro

IPR010987 Glutathione S-transferase, C-terminal-like
IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange
IPR018940 Elongation factor 1 beta central acidic region, eukaryote

PFAM

PF00736
PF10587

PRINTS

PIRSF

SMART

SM00888

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P24534