InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PAX3

Summary

InnateDB Protein

IDBP-246410.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAX3

Protein Name

paired box 3

Synonyms

CDHS; HUP2; WS1; WS3;

Species

Homo sapiens

Ensembl Protein

ENSP00000375921

InnateDB Gene

IDBG-82144 (PAX3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	24 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0071837	HMG box domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001755	neural crest cell migration
GO:0001843	neural tube closure
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006915	apoptotic process
GO:0007507	heart development
GO:0007517	muscle organ development
GO:0007605	sensory perception of sound
GO:0008283	cell proliferation
GO:0008284	positive regulation of cell proliferation
GO:0009887	organ morphogenesis
GO:0014807	regulation of somitogenesis
GO:0016477	cell migration
GO:0021527	spinal cord association neuron differentiation
GO:0021915	neural tube development
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048066	developmental pigmentation
GO:0048663	neuron fate commitment
GO:0060594	mammary gland specification