Version 5.4
Homo sapiens Protein: LGALS14
Summary
InnateDB Protein IDBP-246444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS14
Protein Name lectin, galactoside-binding, soluble, 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000375905
InnateDB Gene IDBG-50731 (LGALS14)
Protein Structure
UniProt Annotation
Function Binds beta-galactoside and lactose. Strong inducer of T- cell apoptosis. {ECO:0000269PubMed:19497882}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11997112}.
Disease Associations
Tissue Specificity Highly expressed in placenta. {ECO:0000269PubMed:11997112, ECO:0000269PubMed:19497882}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00337
PRINTS
PIRSF
SMART SM00276
SM00908
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TCE9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 56891
UniGene Hs.24236
RefSeq NP_064514
HUGO HGNC:30054
OMIM 607260
CCDS CCDS46073
HPRD 06268
IMGT
EMBL AC006133 AF123762 AF267852 AF367430 AF367431 AF367432 AK312040 BC022257 CH471126 FJ613341 FJ613342
GenPept AAF78953 AAH22257 AAK56284 AAK56285 AAK56286 AAP97241 ACR09643 ACR09644 BAG34977 EAW56913

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca