InnateDB Protein
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IDBP-246873.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PTOV1
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Protein Name
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prostate tumor overexpressed 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000375717
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InnateDB Gene
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IDBG-63628 (PTOV1)
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Protein Structure
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Function |
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. {ECO:0000269PubMed:12598323, ECO:0000269PubMed:15713644, ECO:0000269PubMed:17641689}.
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Subcellular Localization |
Cell membrane. Cytoplasm, perinuclear region. Nucleus. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts.
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Disease Associations |
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Tissue Specificity |
Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. {ECO:0000269PubMed:11313889}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
19
[view]
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Protein-Protein |
19
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021394
Mediator complex, subunit Med25, PTOV activation and synapsin 2
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PFAM |
PF11232
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q86YD1
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PhosphoSite |
PhosphoSite-Q86YD1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
53635
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UniGene |
Hs.587979
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RefSeq |
NP_059128
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HUGO |
HGNC:9632
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OMIM |
610195
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CCDS |
CCDS12782
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HPRD |
17929
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IMGT |
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EMBL |
AF218026
AF238381
AJ617480
AY358168
BC015172
BC042921
CH471177
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GenPept |
AAF70635
AAG17268
AAH15172
AAH42921
AAQ88535
CAE84582
EAW52558
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