Version 5.4
Homo sapiens Protein: ALG5
Summary
InnateDB Protein IDBP-24701.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALG5
Protein Name asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000239891
InnateDB Gene IDBG-24699 (ALG5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 1 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004576 oligosaccharyl transferase activity
GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
GO:0007368 determination of left/right symmetry
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y673
PhosphoSite PhosphoSite-Q9Y673
TrEMBL
UniProt Splice Variant
Entrez Gene 29880
UniGene
RefSeq NP_037470
HUGO HGNC:20266
OMIM 604565
CCDS CCDS9361
HPRD 05193
IMGT
EMBL AF102850 AF161498 AK299085 AL138706 BC012531 CH471075
GenPept AAD41465 AAF29113 AAH12531 BAG61149 CAI14011 EAX08578

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca