InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYADM

Summary

InnateDB Protein

IDBP-247023.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYADM

Protein Name

myeloid-associated differentiation marker

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000375650

InnateDB Gene

IDBG-67806 (MYADM)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Widely expressed. Not detected in thymus. {ECO:0000269PubMed:12075932}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0001933	negative regulation of protein phosphorylation
GO:0010629	negative regulation of gene expression
GO:0030335	positive regulation of cell migration
GO:0030837	negative regulation of actin filament polymerization
GO:0031579	membrane raft organization
GO:0034115	negative regulation of heterotypic cell-cell adhesion
GO:0061028	establishment of endothelial barrier
GO:0072661	protein targeting to plasma membrane
GO:0090038	negative regulation of protein kinase C signaling
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading

Cellular Component

GO:0001726	ruffle
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030864	cortical actin cytoskeleton
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome