Version 5.4
Homo sapiens Protein: KRTAP2-3
Summary
InnateDB Protein IDBP-248081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRTAP2-3
Protein Name keratin associated protein 2-3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000375237
InnateDB Gene IDBG-248079 (KRTAP2-3)
Protein Structure
UniProt Annotation
Function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0045095 keratin filament
Protein Structure and Domains
PDB ID
InterPro IPR002494 Keratin-associated protein
PFAM PF01500
PF13885
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P0C7H8
PhosphoSite PhosphoSite-
TrEMBL Q9BYS0
UniProt Splice Variant
Entrez Gene 85294
UniGene
RefSeq NP_001158724
HUGO HGNC:18906
OMIM
CCDS CCDS54123
HPRD
IMGT
EMBL AC100808 AJ406929 AJ406930 BC063625 BC101147 BC101148 BC101149
GenPept AAH63625 AAI01148 AAI01149 AAI01150 CAC27568 CAC27569

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca