Version 5.4
Homo sapiens Protein: RGL4
Summary
InnateDB Protein IDBP-2481.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGL4
Protein Name ral guanine nucleotide dissociation stimulator-like 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000290691
InnateDB Gene IDBG-2473 (RGL4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasmic vesicle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0016023 cytoplasmic membrane-bounded vesicle
Protein Structure and Domains
PDB ID
InterPro IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
IPR023578 Ras guanine nucleotide exchange factor domain
PFAM PF00617
PRINTS
PIRSF
SMART SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IZJ4
PhosphoSite PhosphoSite-Q8IZJ4
TrEMBL B5MCW5
UniProt Splice Variant
Entrez Gene 266747
UniGene Hs.742524
RefSeq NP_705843
HUGO HGNC:31911
OMIM 612214
CCDS CCDS13811
HPRD 11528
IMGT
EMBL AP000347 AY101396
GenPept AAM51551

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca