InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Srpx

Summary

InnateDB Protein

IDBP-249403.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Srpx

Protein Name

sushi-repeat-containing protein

Synonyms

drs; drs-1; drs-2; mDRS-1; mDRS-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111205

InnateDB Gene

IDBG-486724 (Srpx)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001845	phagolysosome assembly
GO:0006914	autophagy
GO:0034976	response to endoplasmic reticulum stress
GO:0060244	negative regulation of cell proliferation involved in contact inhibition
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0005776	autophagic vacuole
GO:0005783	endoplasmic reticulum

Protein Structure and Domains

PDB ID

MGI:1858306

InterPro

IPR000436 Sushi/SCR/CCP
IPR003410 Hyalin

PFAM

PF00084
PF02494

PRINTS

PIRSF

SMART

SM00032

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9R0M3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

51795

UniGene

Mm.1927

RefSeq

MGI ID

MGI Symbol

Srpx

OMIM

CCDS

HPRD

IMGT

EMBL

AB028049 AB028050 AK034696 BC022572 BX005236

GenPept

AAH22572 BAA87328 BAA87329 BAC28800 CAM18749 CAM18750