Version 5.4
Mus musculus Protein: Raver1
Summary
InnateDB Protein IDBP-249518.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Raver1
Protein Name ribonucleoprotein, PTB-binding 1
Synonyms 1300006N24Rik; AA050359; mKIAA1978;
Species Mus musculus
Ensembl Protein ENSMUSP00000111150
InnateDB Gene IDBG-138828 (Raver1)
Protein Structure
UniProt Annotation
Function Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. {ECO:0000269PubMed:14633994}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11724819}. Cytoplasm {ECO:0000269PubMed:11724819}. Note=Nuclear, in perinucleolar structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts. Associated with myotubes during muscle differentiation.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:11724819, ECO:0000269PubMed:16051233}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1919016
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CW46
PhosphoSite PhosphoSite-Q9CW46
TrEMBL
UniProt Splice Variant
Entrez Gene 71766
UniGene Mm.413764
RefSeq NP_082187
MGI ID 3ZZZ
MGI Symbol Raver1
OMIM
CCDS CCDS40550
HPRD
IMGT
EMBL AK004919 AK039928 AK084478 AK220434 AY275472 BC043698 BC108392
GenPept AAH43698 AAI08393 AAP33691 BAB23670 BAC30481 BAC39194 BAD90266

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca