InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cask

Summary

InnateDB Protein

IDBP-249627.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cask

Protein Name

calcium/calmodulin-dependent serine protein kinase (MAGUK family)

Synonyms

DXPri1; DXRib1; LIN-2; mLin-2; Pals3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000111095

InnateDB Gene

IDBG-133241 (Cask)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	48 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042043	neurexin family protein binding

Biological Process

GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0070509	calcium ion import
GO:0090280	positive regulation of calcium ion import

Cellular Component

GO:0005829	cytosol
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0045202	synapse

Protein Structure and Domains

PDB ID

MGI:1309489

InterPro

IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00625

PRINTS

PIRSF

SMART

SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite