InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Onecut2

Summary

InnateDB Protein

IDBP-250282.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Onecut2

Protein Name

one cut domain, family member 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110798

InnateDB Gene

IDBG-153810 (Onecut2)

Protein Structure

UniProt Annotation

Function

Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001889	liver development
GO:0001952	regulation of cell-matrix adhesion
GO:0002064	epithelial cell development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0009653	anatomical structure morphogenesis
GO:0030335	positive regulation of cell migration
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031016	pancreas development
GO:0031018	endocrine pancreas development
GO:0042384	cilium assembly
GO:0045165	cell fate commitment
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048935	peripheral nervous system neuron development