InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnk2

Summary

InnateDB Protein

IDBP-250330.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Tnk2

Protein Name

tyrosine kinase, non-receptor, 2

Synonyms

Ack; Ack-1; Ack1; Cdgip; Pyk1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110773

InnateDB Gene

IDBG-154521 (Tnk2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016301	kinase activity

Biological Process

GO:0016310

phosphorylation

Cellular Component

GO:0030424	axon
GO:0030425	dendrite
GO:0030426	growth cone
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:1858308

InterPro

IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR009060 UBA-like
IPR015116 Cdc42 binding domain like
IPR021619 EGFR receptor inhibitor Mig-6

PFAM

PF00627
PF09027
PF11555

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-