InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Meig1

Summary

InnateDB Protein

IDBP-250425.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Meig1

Protein Name

meiosis expressed gene 1

Synonyms

Meg1; MLZ-278;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110733

InnateDB Gene

IDBG-133168 (Meig1)

Protein Structure

UniProt Annotation

Function

Essential for spermiogenesis. {ECO:0000269PubMed:1390336, ECO:0000269PubMed:19805151}.

Subcellular Localization

Disease Associations

Tissue Specificity

Several isoforms have been identified differing in their 5'-untranslated exons. These isoforms show different tissue expression. Some are expressed in various tissues, including lung, liver, brain, testis, oviduct and oocytes. Some are testis-specific. {ECO:0000269PubMed:1390336, ECO:0000269PubMed:19805151, ECO:0000269PubMed:20339383}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0007126	meiotic nuclear division
GO:0007283	spermatogenesis
GO:0030154	cell differentiation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1202878

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61845

PhosphoSite

PhosphoSite-

TrEMBL

Q8CF17

UniProt Splice Variant

Entrez Gene

104362

UniGene

Mm.475302

RefSeq

MGI ID

MGI Symbol

Meig1

OMIM

CCDS

CCDS38038

HPRD

IMGT

EMBL

AK007239 AL732620 BC049538 X64455

GenPept

AAH49538 BAC25169 CAA45786