InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Robo4

Summary

InnateDB Protein

IDBP-250463.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Robo4

Protein Name

roundabout homolog 4 (Drosophila)

Synonyms

1200012D01Rik; AI593217;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110700

InnateDB Gene

IDBG-150093 (Robo4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding

Biological Process

GO:0001525	angiogenesis
GO:0030154	cell differentiation
GO:0030336	negative regulation of cell migration

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1921394

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite