InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Itgb5

Summary

InnateDB Protein

IDBP-250523.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Itgb5

Protein Name

integrin beta 5

Synonyms

[b]-5; [b]5; [b]5A; [b]5B; AA475909; AI874634; beta-5; beta5; ESTM23;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110680

InnateDB Gene

IDBG-155751 (Itgb5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005178	integrin binding

Biological Process

GO:0007155	cell adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0007275	multicellular organismal development

Cellular Component

GO:0005925	focal adhesion
GO:0008305	integrin complex
GO:0016020	membrane
GO:0031252	cell leading edge
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:96614

InterPro

IPR002035 von Willebrand factor, type A
IPR002369 Integrin beta subunit, N-terminal
IPR012896 Integrin beta subunit, tail
IPR013111 EGF-like domain, extracellular
IPR014836 Integrin beta subunit, cytoplasmic domain
IPR015812 Integrin beta subunit
IPR016201 Plexin-like fold

PFAM

PF00092
PF00362
PF07965
PF07974
PF08725

PRINTS

PR01186

PIRSF

PIRSF002512

SMART

SM00327
SM00187
SM00423

TIGRFAMs

Post-translational Modifications

Modification

Cross-References