Version 5.4
Mus musculus Protein: Tcf4
Summary
InnateDB Protein IDBP-250623.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Tcf4
Protein Name transcription factor 4
Synonyms 5730422P05Rik; ASP-I2; bHLHb19; E2-2; E2.2; ITF-2; ITF-2b; ITF2; ME2; MITF-2A; MITF-2B; SEF-2; SEF2; SEF2-1; Tcf-4; TFE;
Species Mus musculus
Ensembl Protein ENSMUSP00000110628
InnateDB Gene IDBG-156674 (Tcf4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 48 [view]
Protein-Protein 42 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:98506
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q91YV0
UniProt Splice Variant
Entrez Gene 21413
UniGene Mm.485755
RefSeq XP_006525825
MGI ID
MGI Symbol Tcf4
OMIM
CCDS
HPRD
IMGT
EMBL AC109258 AC157576 AC163095 AC167546 AC169193 AK151433 BC014293 CH466528
GenPept AAH14293 BAE30396 EDL09593

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca