InnateDB Protein
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IDBP-250749.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Enox2
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Protein Name
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ecto-NOX disulfide-thiol exchanger 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110562
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InnateDB Gene
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IDBG-144224 (Enox2)
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Protein Structure
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Function |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide- thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock (By similarity). {ECO:0000250UniProtKB:Q16206}.
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Subcellular Localization |
Cell membrane {ECO:0000250}. Secreted, extracellular space {ECO:0000250}. Note=Extracellular and plasma membrane-associated. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2384799
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R0Z2
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PhosphoSite |
PhosphoSite-Q8R0Z2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
209224
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UniGene |
Mm.398131
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RefSeq |
NP_001258380
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MGI ID |
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MGI Symbol |
Enox2
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OMIM |
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CCDS |
CCDS72377
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HPRD |
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IMGT |
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EMBL |
AK034058
AK041822
BC025915
BC026450
BX294194
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GenPept |
AAH25915
AAH26450
BAC28565
BAC31077
CAM21582
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