InnateDB Protein
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IDBP-250799.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Igsf1
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Protein Name
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immunoglobulin superfamily, member 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110541
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InnateDB Gene
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IDBG-144491 (Igsf1)
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Protein Structure
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Function |
Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin- stimulated transcription (By similarity). {ECO:0000250}.
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Subcellular Localization |
Isoform 1: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 2: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 3: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 4: Secreted {ECO:0000305}.Isoform 5: Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
12 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2147913
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InterPro |
IPR007110
Immunoglobulin-like domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7TQA1
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PhosphoSite |
PhosphoSite-Q7TQA1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
209268
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UniGene |
Mm.405513
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RefSeq |
NP_808583
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MGI ID |
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MGI Symbol |
Igsf1
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OMIM |
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CCDS |
CCDS40967
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HPRD |
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IMGT |
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EMBL |
AK030452
AK129126
AY227771
AY227772
AY227773
AY227774
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GenPept |
AAP57079
AAP57080
AAP57081
AAP57082
BAC26969
BAC97936
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