InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pstpip2

Summary

InnateDB Protein

IDBP-251125.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pstpip2

Protein Name

proline-serine-threonine phosphatase-interacting protein 2

Synonyms

cmo; MAYP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110389

InnateDB Gene

IDBG-160316 (Pstpip2)

Protein Structure

UniProt Annotation

Function

Binds to F-actin. May be involved in regulation of the actin cytoskeleton.

Subcellular Localization

Cytoplasm. Membrane; Peripheral membrane protein.

Disease Associations

Tissue Specificity

Expressed in macrophage-containing tissues, including bone marrow, spleen, liver, kidney, intestine and brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0007010

cytoskeleton organization

Cellular Component

GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1335088

InterPro

IPR001060 FCH domain

PFAM

PF00611

PRINTS

PIRSF

SMART

SM00055

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99M15

PhosphoSite

PhosphoSite-Q99M15

TrEMBL

UniProt Splice Variant

Entrez Gene

19201

UniGene

RefSeq

NP_038859

MGI ID

MGI Symbol

Pstpip2

OMIM

CCDS

CCDS37868

HPRD

IMGT

EMBL

AK132418 AK154724 AK157994 BC002123 BC057654 Y18101

GenPept

AAH02123 AAH57654 BAE21158 BAE32788 BAE34306 CAA77027