InnateDB Protein
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IDBP-251198.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Agbl5
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Protein Name
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ATP/GTP binding protein-like 5
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110344
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InnateDB Gene
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IDBG-146365 (Agbl5)
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Protein Structure
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Function |
Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post- translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/ CCP1, AGBL1/CCP4 and AGBL4/CCP6. {ECO:0000269PubMed:20519502, ECO:0000269PubMed:21074048}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000269PubMed:17244818}. Nucleus {ECO:0000269PubMed:17244818}. Note=Mainly cytoplasmic. Slight accumulation in the nucleus is observed.
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Disease Associations |
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Tissue Specificity |
Highly expressed in testis, and moderately in pituitary, brain, eye and kidney. {ECO:0000269PubMed:17244818}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2441745
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InterPro |
IPR000834
Peptidase M14, carboxypeptidase A
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PFAM |
PF00246
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PRINTS |
PR00765
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PIRSF |
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SMART |
SM00631
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TIGRFAMs |
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Modification |
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SwissProt |
Q09M02
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PhosphoSite |
PhosphoSite-Q09M02
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
231093
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UniGene |
Mm.440364
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RefSeq |
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MGI ID |
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MGI Symbol |
Agbl5
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC109606
AK029676
AK034894
AK035680
AK044195
BC057349
DQ867034
DQ867035
DQ867036
DQ867037
DQ867038
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GenPept |
AAH57349
ABI51953
ABI51954
ABI51955
ABI51956
ABI51957
BAC26559
BAC28871
BAC29150
BAC31813
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