InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ERGIC2

Summary

InnateDB Protein

IDBP-25129.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ERGIC2

Protein Name

ERGIC and golgi 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000353270

InnateDB Gene

IDBG-25127 (ERGIC2)

Protein Structure

UniProt Annotation

Function

Possible role in transport between endoplasmic reticulum and Golgi. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Cycles between the endoplasmic reticulum and the Golgi. PubMed:11445006 states that it localizes to the nucleus; PubMed:17980171 shows a partial localization in the nucleus.

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:11445006}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0016192

vesicle-mediated transport

Cellular Component

GO:0005730	nucleolus
GO:0005789	endoplasmic reticulum membrane
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0043231	intracellular membrane-bounded organelle