Version 5.4
Mus musculus Protein: Fmr1
Summary
InnateDB Protein IDBP-251291.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fmr1
Protein Name fragile X mental retardation syndrome 1 homolog
Synonyms Fmr-1; FMRP;
Species Mus musculus
Ensembl Protein ENSMUSP00000110303
InnateDB Gene IDBG-149366 (Fmr1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0007417 central nervous system development
Cellular Component
GO:0005634 nucleus
GO:0005874 microtubule
GO:0010494 cytoplasmic stress granule
GO:0044297 cell body
GO:0071598 neuronal ribonucleoprotein granule
Protein Structure and Domains
PDB ID MGI:95564
InterPro IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
IPR008395 Agenet-like domain
IPR022034 Fragile X mental retardation protein family
PFAM PF00013
PF13014
PF05641
PF12235
PRINTS
PIRSF
SMART SM00322
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8BPN5
UniProt Splice Variant
Entrez Gene 14265
UniGene Mm.487300
RefSeq
MGI ID
MGI Symbol Fmr1
OMIM
CCDS
HPRD
IMGT
EMBL AC055766 AK053701 AK053829
GenPept BAC35482 BAC35545

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca