Version 5.4
Mus musculus Protein: Cd200r3
Summary
InnateDB Protein IDBP-251406.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd200r3
Protein Name CD200 receptor 3
Synonyms 4733401I18Rik; 4833409J19Rik; AI505817; BB106877; mCD200RLb;
Species Mus musculus
Ensembl Protein ENSMUSP00000110260
InnateDB Gene IDBG-162584 (Cd200r3)
Protein Structure
UniProt Annotation
Function According to PubMed:15187158 isoform 4 is a receptor for the CD200 cell surface glycoprotein. According to PubMed:16081818 isoform 4 is not a receptor for the CD200/OX2 cell surface glycoprotein. Isoform 1, isoform 2 and isoform 3 are involved in the recruitment or surface expression of the TYROBP receptor. Isoform 6, isoform 7 and isoform 8 are not involved in the recruitment or surface expression of the TYROBP receptor. {ECO:0000269PubMed:12960329, ECO:0000269PubMed:15187158, ECO:0000269PubMed:15471863, ECO:0000269PubMed:16081818}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in uterus and bone marrow-derived mast cells (at protein level). Expressed in uterus, spleen, bone marrow-derived dendritic, basophil and mast cells. Expressed in the lung of N.brasiliensis-infected mice. Weakly expressed in brain, testis, lung and thymus. {ECO:0000269PubMed:12960329, ECO:0000269PubMed:15187158, ECO:0000269PubMed:15274657, ECO:0000269PubMed:15471863}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1921853
InterPro IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5UKY4
PhosphoSite PhosphoSite-Q5UKY4
TrEMBL E9Q7T2
UniProt Splice Variant
Entrez Gene 74603
UniGene Mm.297337
RefSeq XP_006522737
MGI ID
MGI Symbol Cd200r3
OMIM
CCDS
HPRD
IMGT
EMBL AC124600 AK014637 AK014671 AK040868 AY230199 AY703837 AY703838 AY703839 AY703840 AY703841 AY703842 BC106838
GenPept AAI06839 AAO84053 AAV40659 AAV40660 AAV40661 AAV40662 AAV40663 AAV40664 BAB29480 BAB29497 BAC30726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca