InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Glp1r

Summary

InnateDB Protein

IDBP-251472.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Glp1r

Protein Name

glucagon-like peptide 1 receptor

Synonyms

GLP-1R; GLP1Rc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110221

InnateDB Gene

IDBG-163217 (Glp1r)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0004967	glucagon receptor activity

Biological Process

GO:0006950	response to stress
GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007218	neuropeptide signaling pathway
GO:0007611	learning or memory
GO:0008016	regulation of heart contraction
GO:0019933	cAMP-mediated signaling
GO:0071377	cellular response to glucagon stimulus

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:99571

InterPro

IPR000832 GPCR, family 2, secretin-like
IPR001879 GPCR, family 2, extracellular hormone receptor domain
IPR003290 GPCR, family 2, glucagon-like peptide-1/glucagon receptor
IPR003292 GPCR, family 2, glucagon-like peptide-1 receptor
IPR017981 GPCR, family 2-like

PFAM

PF00002
PF02793

PRINTS

PR00249
PR01353
PR01355

PIRSF

SMART

SM00008

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt