InnateDB Protein
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IDBP-251489.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tmeff2
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Protein Name
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transmembrane protein with EGF-like and two follistatin-like domains 2
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Synonyms
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4832418D20Rik; 7630402F16Rik; TR-2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110212
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InnateDB Gene
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IDBG-152306 (Tmeff2)
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Protein Structure
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Function |
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Widely expressed in the brain. In the olfactory bulb expressed in mitral cell, granule, and glomerular layers. In the hippocampus expressed in hippocampal cornu ammonis, pyramidal layer, dentate gyrus, and substantia nigra pars compacta. {ECO:0000269PubMed:10903839}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1861735
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InterPro |
IPR002350
Kazal domain
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PFAM |
PF00050
PF07648
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PRINTS |
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PIRSF |
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SMART |
SM00280
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TIGRFAMs |
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Modification |
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SwissProt |
Q9QYM9
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
56363
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UniGene |
Mm.245154
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RefSeq |
XP_006496229
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MGI ID |
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MGI Symbol |
Tmeff2
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB017270
AB041565
AK029307
AK030053
AK076254
AK135038
BC034850
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GenPept |
AAH34850
BAA87898
BAA95049
BAC26385
BAC26760
BAC36276
BAE22393
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