InnateDB Protein
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IDBP-251507.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Zfp467
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Protein Name
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zinc finger protein 467
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Synonyms
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1190001I08Rik; AB041616; AI426952; AV017623; EZI; Znf467;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110208
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InnateDB Gene
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IDBG-144418 (Zfp467)
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Protein Structure
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Function |
Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex. {ECO:0000269PubMed:12426389, ECO:0000269PubMed:21123171}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:12426389}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1916160
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q8JZL0
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PhosphoSite |
PhosphoSite-Q8JZL0
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TrEMBL |
B2RU53
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UniProt Splice Variant |
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Entrez Gene |
68910
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UniGene |
Mm.2464
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RefSeq |
NP_065614
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MGI ID |
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MGI Symbol |
Zfp467
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OMIM |
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CCDS |
CCDS51764
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HPRD |
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IMGT |
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EMBL |
AB041616
AB076746
AK033146
BC029859
BC140975
CH466597
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GenPept |
AAH29859
AAI40976
BAA95099
BAC00997
BAC28171
EDK98529
EDK98530
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