Version 5.4
Mus musculus Protein: Dppa2
Summary
InnateDB Protein IDBP-251572.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dppa2
Protein Name developmental pluripotency associated 2
Synonyms 2410088E07Rik; C80932; D19Mgi18; ECAT15-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000110183
InnateDB Gene IDBG-216010 (Dppa2)
Protein Structure
UniProt Annotation
Function Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes. {ECO:0000269PubMed:21896782}.
Subcellular Localization Nucleus {ECO:0000269PubMed:21896782}.
Disease Associations
Tissue Specificity Not detected in adult tissues. {ECO:0000269PubMed:12620990}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003682 chromatin binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019827 stem cell maintenance
GO:0031060 regulation of histone methylation
GO:0060484 lung-associated mesenchyme development
GO:2000648 positive regulation of stem cell proliferation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2157523
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CWH0
PhosphoSite PhosphoSite-Q9CWH0
TrEMBL B2RQ54
UniProt Splice Variant
Entrez Gene 73703
UniGene Mm.27857
RefSeq NP_082891
MGI ID
MGI Symbol Dppa2
OMIM
CCDS CCDS37350
HPRD
IMGT
EMBL AF490346 AK010743 AK145645 AK145760 AK163375 AK167211 AY561246 BC137768 CH466521
GenPept AAI37769 AAO84504 AAS68013 BAB27153 BAE26562 BAE26632 BAE37324 BAE39338 EDK98092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca