InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dzip3

Summary

InnateDB Protein

IDBP-251601.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dzip3

Protein Name

DAZ interacting protein 3, zinc finger

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110161

InnateDB Gene

IDBG-164649 (Dzip3)

Protein Structure

UniProt Annotation

Function

E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003779	actin binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0019902	phosphatase binding
GO:0046872	metal ion binding