InnateDB Protein
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IDBP-251638.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hnmt
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Protein Name
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histamine N-methyltransferase
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000110142
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InnateDB Gene
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IDBG-141972 (Hnmt)
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Protein Structure
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Function |
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
Accession |
GO Term |
GO:0008170
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N-methyltransferase activity
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GO:0046539
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histamine N-methyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2153181
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InterPro |
IPR016673
Histamine N-methyltransferase
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
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PFAM |
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PRINTS |
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PIRSF |
PIRSF016616
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91VF2
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PhosphoSite |
PhosphoSite-Q91VF2
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TrEMBL |
A2AQK4
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UniProt Splice Variant |
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Entrez Gene |
140483
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UniGene |
Mm.406925
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RefSeq |
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MGI ID |
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MGI Symbol |
Hnmt
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OMIM |
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CCDS |
CCDS15731
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HPRD |
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IMGT |
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EMBL |
AB070523
AB070524
AB444950
AB444951
AF297037
AF297039
AF297040
AF297041
AF297042
AF297043
AF298150
AK050129
AK160131
BC033928
CH466542
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GenPept |
AAH33928
AAL09305
AAL09306
BAB84318
BAB84320
BAC34081
BAE35648
BAG66245
BAG66246
EDL08158
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