InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il1rn

Summary

InnateDB Protein

IDBP-251674.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Il1rn

Protein Name

interleukin 1 receptor antagonist

Synonyms

F630041P17Rik; IL-1ra;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110129

InnateDB Gene

IDBG-142372 (Il1rn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005149	interleukin-1 receptor binding
GO:0005152	interleukin-1 receptor antagonist activity

Biological Process

GO:0001960	negative regulation of cytokine-mediated signaling pathway
GO:0006629	lipid metabolic process
GO:0030073	insulin secretion

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0031982	vesicle

Protein Structure and Domains

PDB ID

MGI:96547

InterPro

IPR000975 Interleukin-1 family
IPR003294 Interleukin-1 alpha/beta
IPR003297 Interleukin-1 receptor antagonist / Interleukin-36
IPR008996 Cytokine, IL-1-like

PFAM

PF00340

PRINTS

PR00264
PR01357
PR01360

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite