Version 5.4
Mus musculus Protein: Tprn
Summary
InnateDB Protein IDBP-251989.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tprn
Protein Name taperin
Synonyms C430004E15Rik; C87750;
Species Mus musculus
Ensembl Protein ENSMUSP00000109975
InnateDB Gene IDBG-144709 (Tprn)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell projection, stereocilium {ECO:0000269PubMed:20170899}. Note=Localized prominently at the taper regions of hair cell stereocilia.
Disease Associations
Tissue Specificity Expressed in the sensory epithelia of the organ of Corti and vestibular end organs and, to a lesser extent, in Reisner's membrane and the spiral ligament (at protein level). At postnatal day 2, expression is detected in cochlea, liver, brain, kidney, heart and lung. {ECO:0000269PubMed:20170898, ECO:0000269PubMed:20170899}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0019902 phosphatase binding
Biological Process
GO:0007605 sensory perception of sound
Cellular Component
GO:0032420 stereocilium
Protein Structure and Domains
PDB ID MGI:2139535
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AI08
PhosphoSite PhosphoSite-A2AI08
TrEMBL
UniProt Splice Variant
Entrez Gene 97031
UniGene Mm.486304
RefSeq NP_780495
MGI ID
MGI Symbol Tprn
OMIM
CCDS CCDS15759
HPRD
IMGT
EMBL AK082888 AK165772 AK171799 AL732309 BC024573 BC055478 BC089508
GenPept AAH24573 AAH55478 AAH89508 BAC38669 BAE38373 BAE42670 CAM14678

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca