InnateDB Protein
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IDBP-252154.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rbm11
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Protein Name
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RNA binding motif protein 11
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109891
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InnateDB Gene
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IDBG-171345 (Rbm11)
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Protein Structure
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Function |
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus, nucleoplasm {ECO:0000250}. Nucleus speckle {ECO:0000250}. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Selectively expressed in brain, cerebellum and testis, and to a lower extent in kidney. {ECO:0000269PubMed:21984414}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2447622
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q80YT9
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
224344
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UniGene |
Mm.273214
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RefSeq |
NP_938044
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MGI ID |
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MGI Symbol |
Rbm11
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OMIM |
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CCDS |
CCDS37377
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HPRD |
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IMGT |
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EMBL |
AC166995
AK039297
BC050779
CH466521
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GenPept |
AAH50779
BAC30309
EDK98269
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