InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lingo1

Summary

InnateDB Protein

IDBP-252158.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lingo1

Protein Name

leucine rich repeat and Ig domain containing 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109894

InnateDB Gene

IDBG-168858 (Lingo1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005154	epidermal growth factor receptor binding
GO:0005515	protein binding

Biological Process

GO:0021954	central nervous system neuron development
GO:0031175	neuron projection development
GO:0043491	protein kinase B signaling
GO:0048715	negative regulation of oligodendrocyte differentiation

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1915522

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set

PFAM

PF01462
PF00560
PF13504
PF13855
PF07679

PRINTS

PIRSF

SMART

SM00013
SM00369
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite