InnateDB Protein
|
IDBP-252230.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Ablim2
|
Protein Name
|
actin-binding LIM protein 2
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000109848
|
InnateDB Gene
|
IDBG-157552 (Ablim2)
|
Protein Structure
|
|
Function |
May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
|
Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:17194709}. Note=In skeletal muscle, sarcomeric or cosarcomeric localization.
|
Disease Associations |
|
Tissue Specificity |
Expressed in brain. Highly expressed in caudate/putamen, moderately expressed in the olfactory bulb. In the hippocampus, expressed in the CA1, CA2 and CA3 fields. In the cerebellum, expressed in Purkinje cells. {ECO:0000269PubMed:17194709}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
5 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0006351
|
transcription, DNA-templated
|
GO:0030036
|
actin cytoskeleton organization
|
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter
|
|
Cellular Component |
|
PDB ID |
MGI:2385758
|
InterPro |
IPR001781
Zinc finger, LIM-type
|
PFAM |
PF00412
|
PRINTS |
|
PIRSF |
|
SMART |
SM00132
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8BL65
|
PhosphoSite |
PhosphoSite-Q8BL65
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
231148
|
UniGene |
Mm.408756
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Ablim2
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AJ748602
AJ748603
AK046243
AK046879
AK082707
AY274116
BC141125
|
GenPept |
AAI41126
AAP23233
BAC32651
BAC32905
BAC38580
CAG38377
CAG38378
|
|
|