InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ablim2

Summary

InnateDB Protein

IDBP-252236.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ablim2

Protein Name

actin-binding LIM protein 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109843

InnateDB Gene

IDBG-157552 (Ablim2)

Protein Structure

UniProt Annotation

Function

May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17194709}. Note=In skeletal muscle, sarcomeric or cosarcomeric localization.

Disease Associations

Tissue Specificity

Expressed in brain. Highly expressed in caudate/putamen, moderately expressed in the olfactory bulb. In the hippocampus, expressed in the CA1, CA2 and CA3 fields. In the cerebellum, expressed in Purkinje cells. {ECO:0000269PubMed:17194709}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003779	actin binding
GO:0008270	zinc ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0007010	cytoskeleton organization
GO:0030036	actin cytoskeleton organization
GO:0045944	positive regulation of transcription from RNA polymerase II promoter