Version 5.4
| Homo sapiens Protein: MMP26 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-25254.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | MMP26 | ||||||||
| Protein Name | matrix metallopeptidase 26 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000300762 | ||||||||
| InnateDB Gene | IDBG-25250 (MMP26) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. Is also able to activate progelatinase B. | ||||||||
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed specifically in uterus and placenta. Is also widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001818
Peptidase M10, metallopeptidase IPR002477 Peptidoglycan binding-like IPR006026 Peptidase, metallopeptidase IPR021190 Peptidase M10A |
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| PFAM |
PF00413
PF01471 |
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| PRINTS |
PR00138
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| PIRSF | |||||||||
| SMART |
SM00235
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9NRE1 | ||||||||
| PhosphoSite | PhosphoSite-Q9NRE1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56547 | ||||||||
| UniGene | Hs.204732 | ||||||||
| RefSeq | NP_068573 | ||||||||
| HUGO | HGNC:14249 | ||||||||
| OMIM | 605470 | ||||||||
| CCDS | CCDS7752 | ||||||||
| HPRD | 05683 | ||||||||
| IMGT | |||||||||
| EMBL | AF230354 AF248646 AF291664 AF291665 AJ251531 BC101541 BC101543 | ||||||||
| GenPept | AAF80180 AAF82359 AAG00603 AAG02470 AAI01542 AAI01544 CAC08821 | ||||||||