InnateDB Protein
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IDBP-252544.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Elmod3
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Protein Name
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ELMO/CED-12 domain containing 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109703
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InnateDB Gene
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IDBG-157734 (Elmod3)
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Protein Structure
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Function |
Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity. {ECO:0000250}.
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Subcellular Localization |
Cell projection, stereocilium {ECO:0000269PubMed:24039609}. Cell projection, kinocilium {ECO:0000269PubMed:24039609}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:24039609}. Note=Also present in the cuticular plate of auditory hair cells. In the organ of Corti, in inner hair cells, expressed along the length of the stereocilia, but excluded from the very tip. Colocalizes with F-actin cytoskeleton.
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Disease Associations |
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Tissue Specificity |
Both isoform 1 and isoform 2 are widely expressed. {ECO:0000269PubMed:24039609}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2445168
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InterPro |
IPR006816
Engulfment/cell motility, ELMO
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PFAM |
PF04727
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91YP6
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PhosphoSite |
PhosphoSite-Q91YP6
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TrEMBL |
D3Z5B5
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UniProt Splice Variant |
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Entrez Gene |
232089
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UniGene |
Mm.167232
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RefSeq |
NP_659166
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MGI ID |
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MGI Symbol |
Elmod3
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OMIM |
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CCDS |
CCDS20243
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HPRD |
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IMGT |
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EMBL |
AC125039
AC154002
AK049155
AK084010
AK164974
BC016193
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GenPept |
AAH16193
BAC33574
BAC39096
BAE37985
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