InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dlg3

Summary

InnateDB Protein

IDBP-253250.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Dlg3

Protein Name

discs, large homolog 3 (Drosophila)

Synonyms

Dlgh3; mKIAA1232; SAP102;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109364

InnateDB Gene

IDBG-162702 (Dlg3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0001736	establishment of planar polarity
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005923	tight junction
GO:0032281	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex

Protein Structure and Domains

PDB ID

MGI:1888986

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00018
PF14604
PF00595
PF13180
PF00625
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00326
SM00228
SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt