InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc7a3

Summary

InnateDB Protein

IDBP-253334.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc7a3

Protein Name

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

Synonyms

Atrc3; CAT-3; CAT3; SLC7A1; SLC7A2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109339

InnateDB Gene

IDBG-163161 (Slc7a3)

Protein Structure

UniProt Annotation

Function

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. {ECO:0000269PubMed:9334265}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed in adult brain and in a wide variety of embryonic tissues. {ECO:0000269PubMed:9334265}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015171	amino acid transmembrane transporter activity
GO:0015181	arginine transmembrane transporter activity
GO:0015189	L-lysine transmembrane transporter activity
GO:0015326	cationic amino acid transmembrane transporter activity

Biological Process

GO:0003333	amino acid transmembrane transport
GO:0006810	transport
GO:0006865	amino acid transport
GO:0015809	arginine transport
GO:0015819	lysine transport
GO:0055085	transmembrane transport
GO:1902475	L-alpha-amino acid transmembrane transport