Version 5.4
Mus musculus Protein: Prrx2
Summary
InnateDB Protein IDBP-253560.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Prrx2
Protein Name paired related homeobox 2
Synonyms Prx2; S8;
Species Mus musculus
Ensembl Protein ENSMUSP00000109222
InnateDB Gene IDBG-157003 (Prrx2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0006355 regulation of transcription, DNA-templated
GO:0030326 embryonic limb morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0045880 positive regulation of smoothened signaling pathway
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0048844 artery morphogenesis
GO:0051216 cartilage development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:98218
InterPro IPR001356 Homeobox domain
IPR003654 OAR domain
IPR009057 Homeodomain-like
PFAM PF00046
PF03826
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9CY80
UniProt Splice Variant
Entrez Gene 20204
UniGene Mm.1802
RefSeq
MGI ID
MGI Symbol Prrx2
OMIM
CCDS
HPRD
IMGT
EMBL AK019971 AL844532
GenPept BAB31942

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca